Longevity Science · 10 min read · January 8, 2026
Longevity Peptides in Published Research
Reading the literature on NAD+, Epitalon, and related longevity-adjacent compounds.
Dr. Mira Halden
Chief Scientific Officer
The NAD+ story
Cellular NAD+ pools decline with age. That single finding — replicated across many tissues and species — has anchored a decade of longevity research. The question the literature now asks is not whether NAD+ declines, but whether restoring it produces durable, system-level effects.
Preclinical models show that sirtuin activity, mitochondrial respiration, and DNA-damage-response markers all respond to NAD+ precursor supplementation. Translation to human studies is earlier in its arc; the published record is growing but modest.
Epitalon and telomere biology
Epitalon has a narrower literature than NAD+ but a longer one. Russian and Eastern European research groups have published consistently on pineal-gland regulation and telomerase expression in cell-culture models for more than two decades.
The Western literature is lighter. A careful reader holds both: the consistency of the early work, and the limited independent replication in more recent years.
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Understanding Research Peptide Purity
Purity is the most misunderstood number on a Certificate of Analysis. Here is what it measures, what it does not, and how to read it critically.
Peptide Fundamentals · 6 min
Reading a Certificate of Analysis
A good CoA is four documents bundled into one. Here is what each of them is for, and what to look for when the paperwork feels thin.
Research Protocols · 9 min
Protocols for Reconstitution and Storage
Reconstitution is where most peptide studies lose their rigor. Here is a working protocol for keeping samples stable from the lyophilized form to the assay.
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